Does transcription go in the 3' - 5' direction or 5' - 3' direction?

Science Protein biosynthesis

Question:

Transcription:

Transcription is the first step in protein synthesis where a gene on DNA is copied into a strand of mRNA by RNA polymerase enzymes.

Directionality of Transcription:

The chemical structure of DNA determines how base pairs can be added to an elongating RNA strand during transcription.
On the 5' end of the DNA is a carbon atom bound to a phosphate group. This molecule is not available to form bonds with other atoms.
The 3' end of the DNA strand contains a carbon atom bound to a hydroxyl group (-OH). This group can form bonds with other atoms through a process called dehydration synthesis. This reaction attaches new molecules and releases water as a result.

Answer and Explanation:1

Transcription always occurs in the 5' - 3' direction because it must be antiparallel to the complementary strand it is base paired with. So that means it will start at the 3' end of its complementary strand and proceed in the 5' - 3' direction as it copies the gene on DNA into mRNA.

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Does transcription go in the 3' - 5' direction or 5' - 3' direction? | Homework.Study.com (2024)