Istanbul. (Disputed)
Explanation:
According to many geographical sources Istanbul is the city located at the center of the world. However, it is not a very clearly established fact.
In the maps of the early world, Jerusalem was known to be the central city of the world due to its location.
Neil Armstrong once proved that Mecca is the centrally located city on Earth.
Some sources also state that Quito, the capital of a country that was named after the Equator, lies in the Southern Hemisphere is the centre of the world.