Humira was the leading medicine in the United States based on sales in 2022, generating 18.6 billion U.S. dollars in revenue. The branded drug – used to treat, for example, arthritis – has topped revenue rankings for a number of years and generated around six billion U.S. dollars more than second ranked Keytruda.
AbbVie in healthy position thanks to sales of top products
Spending on Humira in the United States more than doubled between 2014 and 2018. The biopharmaceutical company responsible for the production of the drug, AbbVie, generated global revenues of around 58 billion U.S. dollars in 2022. Humira, Imbruvica, and Skyrizi were AbbVie’s top three products based on sales in that year, combining for more than half of the company’s total revenue – Humira’s worldwide revenue alone accounted for more than a third.
How much money is spent on medicines in the United States?
In the United States, total nominal spending on medicines exceeded 600 billion U.S. dollars in 2022, with sales of branded drugs accounting for around 84 percent of the market. Drugs can be categorized in several ways, but a common method is to group them by what they are used to treat. In the United States, cancer, diabetes, and immunology are among the leading therapeutic categories based on sales.
FAQs
The four best-selling products in 2022 were biotech: Comirnaty, Spikevax, Humira, and Keytruda. Although not a drug in the classic sense, biotech-derived mRNA-vaccine Comirnaty was the best-selling pharmaceutical product of all times already in 2021, based on annual sales.
What is the top pharma drug by sales in 2022? ›
Other COVID-19 therapies in the fourth and fifth positions
| Drug name | Manufacturer(s) | 2022 Sales |
|---|
| 1. Comirnaty COVID-19 vaccine | Pfizer/BioNTech | $55,918,791,640 |
| 2. Humira (adalimumab) | AbbVie | $21,237,000,000 |
| 3. Keytruda (pembrolizumab) | Merck | $20,937,000,000 |
| 4. Paxlovid | Pfizer | $18,933,000,000 |
46 more rowsApr 18, 2023
Atorvastatin calcium was the most prescribed drug in 2022, with 2.8% of claims. Atorvastatin is a statin used to treat abnormal lipid levels and prevent cardiovascular disease.
What are the top selling prescription drugs? ›
Best selling pharmaceuticals of U.S. market
| Rank | Drug | Trade name |
|---|
| 1 | adalimumab | Humira |
| 2 | apixaban | Eliquis |
| 3 | etanercept | Enbrel |
| 4 | ustekinumab | Stelara |
1 more rowExamples of blockbuster drugs include Vioxx, Lipitor, and Zoloft. Blockbuster drugs are commonly used to treat common medical problems like high cholesterol, diabetes, high blood pressure, asthma, and cancer.
What is the highest sold heart medicine in the world? ›
Sales of top cardiovascular drugs worldwide 2023
For 2023, global sales estimates for cardiovascular drugs revealed Eliquis as the top-selling cardiac medication, reaching approximately 12 billion U.S. dollars.
What is AbbVie's top-selling drug? ›
AbbVie's key product revenues 2022-2023
In 2023, once again, the company's top revenue generating drug was Humira. In that year, Humira generated about 14.4 billion U.S. dollars in revenue for AbbVie.
What is the #1 most prescribed drug? ›
The Top 300 Drugs of 2021
| Rank | Drug Name | Total Prescriptions (2021) |
|---|
| 1 | Atorvastatin | 116,702,335 |
| 2 | Metformin | 91,151,043 |
| 3 | Levothyroxine | 89,309,050 |
| 4 | Lisinopril | 88,272,557 |
93 more rowsSep 12, 2021
Here's a list of the top 10 most prescribed drugs in the US, as well as some information about the conditions they treat. The top 10 most prescribed drugs are atorvastatin, levothyroxine, lisinopril, metformin, metoprolol, amlodipine, albuterol, omeprazole, losartan, and gabapentin.
Where does the US get most of its prescription drugs? ›
China, India, and Mexico accounted for 57% of all pharmaceutical imports by weight in 2021. Over the past decade to 2021, pharmaceutical imports have nearly doubled (increased by 89%) and increased by a factor of six in the past twenty years.
The federal government is the largest purchaser of prescription drugs in the United States; it purchases drugs either directly or by subsidizing federal health insurance programs.
What is the best selling statin drug? ›
They include:
- Atorvastatin (Lipitor).
- Fluvastin (Lescol XL).
- Lovastatin (Altoprev).
- Pitavastatin (Livalo).
- Pravastatin.
- Rosuvastatin (Crestor).
- Simvastatin (Zocor).
1. Penicillin (1942) Penicillin was first developed in 1928 but started to be used in 1942. As the first official antibiotic, it marked a turning point in human history and led the way in the treatment of numerous bacterial diseases.
What is the most abused drug in the Western world? ›
Cannabis users comprise the largest number of illicit drug users (129-190 million people). Amphetamine-type stimulants are the second most com- monly used illicit drugs, followed by opiates and cocaine. However, in terms of harm associated with use, opiates would be ranked at the top.
What is the blockbuster drug in 2024? ›
1. KarXT. You'd be forgiven for scratching your head at what Evaluate believes will be the biggest drug launch of 2024, in terms of sales potential by 2028, and at its maker Karuna Therapeutics.
What is a mega blockbuster drug? ›
A blockbuster drug is a medication that generates annual sales of over $1 billion. Weight-loss medications like Ozempic and Wegovy are among the latest drugs to reach blockbuster status. Most blockbuster drugs treat chronic conditions that affect many people.
What is the most profitable pharmaceutical drug ever? ›
Which Is the Most Profitable Pharmaceutical Drug Ever? The most lucrative pharmaceutical drug in the industry is LIPITOR, developed, marketed, and sold by the PFIZER corporation. During its patent protection period, LIPITOR amassed a staggering $131 billion in sales.
Which pharmaceutical company has the highest revenue? ›
From Johnson & Johnson to Bristol Myers Squibb (BMS), Pharmaceutical Technology lists the top ten pharmaceutical companies in 2023, based on their revenues.
- Johnson & Johnson- $85.2bn.
- F. ...
- Merck & Co – $60.1bn.
- Pfizer – $58.5bn.
- AbbVie – $54.3bn.
- Bayer – $51.9bn.
- Sanofi– $46.9bn.
- AstraZeneca – $45.8bn.
Many of the leading pharma companies come from the United States, and, therefore, it is no surprise that the country has the largest national pharmaceutical market worldwide.
What is the largest pharma deal ever? ›
As of early 2024, the largest deal in pharmaceutical industry history was Pfizer's acquisition of Warner-Lambert for nearly 90 billion U.S. dollars in 2000. A further two deals in the rankings involve the American company Pfizer: its acquisitions of rival firms Pharmacia (2002) and Wyeth (2009).
